There is wide acceptance within the cancer research community that the human tumor microenvironment and knowledge of the immune response within this environment holds the key to understanding the protective tumor immunity and to explaining why some cancer patients respond well to immune therapy and others do not. It has become increasingly apparent that the dynamic interaction between tumor cells and patient's immune cells, particularly T cells, is responsible for the tumor's escape from immune surveillance that ultimately results in tumor progression and metastasis.*
*Zou, W., Wolchok, J.D. and Chen, Lieping, Science Translational Medicine, March 2016, 8:328, pp1-14.
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